'I-28Sfuuy-WR10okMSia3VYeZTm2RHA2LZDel59TlF8' name='google-site-verification'/>www ghs.google.com 6dseurqgapmn gv-v6egtfduggmq3k.dv.googlehosted.com Autismwarriormama: 27 Things You Should Know About Seizure Medications

Living with Autism


March 18, 2011

27 Things You Should Know About Seizure Medications

Studies show about 20-30% of people with autism have epilepsy. If you are a parent, teacher, caregiver, relative, friend or advocate of someone with autism and epilepsy, you need to read this. If you're a person with epilepsy read this. Information is taken directly from reviews of epilepsy research.

1. Lamictal (lomotrigine) can INCREASE myoclonic seizures (especially NOCTURNAL myoclonus)

2. Taking Tylenol may lower Lamictal levels

3. Lamictal is good for Frontal Lobe Epilepsy

4. Keppra (levetiracetam) can DECREASE myoclonic seizures

5. Taking B-Vitamins can mitigate Keppra's infamous adverse behavioral side effects

6. Keppra is good for hippocampal related seizures

7. Depakote linked to hyperammonemia (dangerous levels of ammonia in your body)

8. Klonopin (clonazepam) is a benzodiazepine to help treat ATONIC (drop) seizures

9. Best drugs for atonic seizures: Depakote, Lamictal, Topamax (topiramate)

10.  Best drugs for myoclonic seizures: Keppra, Klonipin, Tompamax. 

11. Worst drugs for myoclonic seizures: Tegretol (carbamazepine), Dilantin (phenytoin), Phonobarbital and Sabril (Vigabatrin).

12. Topamax best for temporal lobe epilepsy. 

13. Klonipin sometimes helpful for REM sleep disorder related epilepsy. 

14. Higher doses of Klonipin and Lamictal can increase tonic-clonic seizure activity in some people.

15. Generic seizure medications can kill you. They are not the same as drugs first approved by FDA. Generic formulations and manufacturers change frequently. God only knows what you're really getting and that's dangerous when someone is taking a seizure medication.
See: www.consumerwarningnetwork.com/.../warning-generic-drugs-not-always-equivalent-to-name

A High functioning autistic person wrote, "It is absolute BULL%$# that a generic medication is always the same as the brand .... Probably not. The same wasn't true for other classes of medications". Source:...www.crazymeds.us/BvsG.html

Source: Brand Name and Generic Drugs NOT equivalent http://www.uspharmacist.com/content/d/pharmacy%20law/c/30046/

16. 5 HT1A receptors appear low in people with epilepsy. Drugs that target 5HT1A receptors: Partial agonists: Cannabidiol, Lamictal,Trazodone and Ginkgo Biloba.

17. Tonic Clonic seizures aren't they only type of seizure that can be "status" (on going). Example: People can have status myoclonus or absence seizures.

18. Taking seizure medication depletes CHOLINE. Replace choline by eating egg yolks, taking Huperzine A or DMAE. Consult your doctor.

19. Choline deficiency places undue stress on liver.

20. Choline has anti-inflammatory properties. Lack of choline=higher inflammation-elevated levels of homocysteine.

21. Seizure medications deplete body of Folic Acid, Vitamin D and Carnitine

22. Cognitive decline caused by seizure drugs like Topamax and Depakote can be thwarted by natural herbs like Bacopa Monnieri.

23. Bacopa Monnieri can also reverse benzodiazepine fog.

24. NREM parasomnia may co-exist with epilepsy

25. Studies show Ginkgo Biloba, a nootropic with antioxidant properties, reduced seizure activity in rats. Go Ben. Other studies showed it increased seizures in human. Go figure.

26. Piracetam is a nootropic agent commonly prescribed in foreign countries, used to treat autism and epilepsy. Studies show piracetam modulates acetylcholine levels, increases cognition and has few side effects. Too bad it's not approved in USA.

27. Medical marijuana high in CBDs helps people with epilepsy. At first, I thought this was utter bull and just another ploy to get non-pot heads to accept medical cannabis. However, upon careful analysis, with an open mind, it appears that people with epilepsy are low in 5 HT 1a receptors. Cannabis high in "Cannabidiol" appears to act as a 5 HT1 a, receptor agonist (increases action) an action that is involved in it anxiolytic and neuroprotective effects. This is a good thing for people with epilepsy.

27. Recent studies indicate nicotine can be used to help adults suffering from autosomal dominant nocturnal frontal lobe epilepsy. The same areas that cause seizures in that form of epilepsy are responsible for processing nicotine in the brain.Source: ^ "Nicotine as an antiepileptic agent in ADNFLE: An n-of-one study". http://www.cnsforum.com/commenteditem/3c5dccdc-27fb-4b80-9516-ab81e3e4ea6c/default.aspx.

In short, finding effective treatments for individuals with autism, seizures and/or self-injurious behavior, is a puzzle, an enigma, a brain teaser, a complex problem--one that tests the resolve and skills of all involved to recognize patterns, ask questions, make discoveries and use deductive reasoning--- to put together pieces in a logical manner and achieve desired outcome: Controlling Seizures. And maximizing  full potential of the autistic individual.

*Always consult a doctor when seeking changes or stoping medications. Never stop seizure medication abruptly. Consult a neurologist if you have any questions, concerns about seizure medication or epilepsy.

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Anonymous said...

I am almost afraid I've developed a tendency to sleep-blog... the parallels are so close it's spooky. One question: been fighting the generic battle for some time (mainly because some are apparantly coming in from off-shore production facilities) - can you give any citation for #15?

KC's Warrior Mama said...

Would you mind if I post this on my blog, citing your blog as the source?

Gilda Sanchez said...

Hi Kim:

Have you had any success with Nootropics for Jamey? Piracetam has some interesting qualities but can these cognitive enhancers improve executive functioning for those with severe autism? I looked up Phenibut, an anti-anxiety supplement. Could this help improve anxiety and reduce stress?

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