'I-28Sfuuy-WR10okMSia3VYeZTm2RHA2LZDel59TlF8' name='google-site-verification'/>www ghs.google.com 6dseurqgapmn gv-v6egtfduggmq3k.dv.googlehosted.com Autismwarriormama: Does Vitamin B-6 dysfunction play a role in autism, epilepsy and self-injurious behavior?

Living with Autism


September 14, 2015

Does Vitamin B-6 dysfunction play a role in autism, epilepsy and self-injurious behavior?

Award Winning Non-Fiction Blogs - BlogCatalog Blog DirectoryAnalysis and Facts:

The majority of vitamin B6 dependent seizures appear from a deficiency in enzyme a-aminoadipic semialdehyde dehydrogenase.

This appears to cause a depletion of B6, pyridoxal phosphate, the active form of B6.

Clinical features may include chronic breakthrough seizures, self-injurious behavior in autistic patients.

Diagnostic testing to help illuminate pathology of SIB and EPILEPSY in autistic patients may include: Pyridoxine trial. Plasma and cerebrospinal fluid pipecolic acid. Urine a-aminoadipic semialdehyde. ALDH7A1 sequencing.

The disorder is rare.

Linked to intractable seizures in patients with autism and self-injurious behavior.

Disorder basically inhibits binding of B6 to glutamic acid, which is needed for GABA biosynthesis.

Source: (Journal of Child Neurology 2000: 15, 763-765)

I lost faith in a lot of autism research studies, but this is an area where I strongly believe the most hope has been offered in many years of "autism research".

No doubt: MORE FUNDING needed for researchers studying the link between metabolic and mitochrondrial issues in autism, epilepsy and aberrant behaviors--- is desperately needed.

Kim Oakley


Lindsey said...

Hi Kim,

I am with a company, Revolution Advisors, and we would like to use one of your YouTube video's for a training event. We were hoping you would allow us to use the video. Please let me know if you need to know the exact video.


Lindsey said...

Hi Kim,

The company I work for would like to use one of your videos that you posted on YouTube for a training event. Please let me know if this is possible and if you would like information on the company that I work for.

Thank you!

Anon said...

Hello! First off, you're a wonderful advocate and educator. Secondly, have you heard of Dr. David Berger of Wholisitic Pediatrics and Family Care in Tampa? He is an MD that also does holistic medicine and is an ASD expert. He has done wonders for our child.

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